The heat-shock response.

PERSPECTIVES AND SUMMARY .............................................................. 1151 CHARACTERIZATION OF THE RESPONSE .................................................. 1153 Comparison: Different Organisms and Stages of Development ........................... 1153 The Proteins Induced by Heat .................................................................. 1155 RNAs Induced by Heat ........ : .................................................................. 1167 OTHER INDUCTIONS F HSPs .................................................................. 1168 Developmental Inductions ....................................................................... 1168 Other Inducers ..................................................................................... 1169 Is There a Common Mechanism? .............................................................. 1170 GENOME ORGANIZATION ....................................................................... 1172 REGULATION OF THE RESPONSE ............................................................. 1173 Transcription ....................................................................................... 1173 Translation ......................................................................................... 1177 RIgA Processing ................................................................................... 1178 TOLERANCE TO HEAT AND OTHER FORMS OF STRESS .............................. 1179 Heat-Induced Lethality and Thermotolerance ................................................ 1179 Phenocopies ........................................................................................ 1182 CONCLUDING REMARKS ........................................................................ 1184